| Navigating Veno-Occlusive Disease (VOD)/Sinusoidal Obstruction Syndrome (SOS): Guidelines, Tools, an |
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In this Educator Module, Ashley Jacks, PA-C, of Fred Hutchinson Cancer Center, provides a comprehensive overview of veno-occlusive disease (VOD), also known as sinusoidal obstruction syndrome (SOS), a rare but life-threatening complication following hematopoietic stem cell transplantation. This module details the clinical and laboratory findings and compares traditional (Baltimore, Seattle) and contemporary (EBMT, Cairo/Cooke) diagnostic criteria for VOD/SOS. The module also reviews pathogenesis and various risk factors and discusses severity grading. It highlights the crucial need for prompt recognition and early therapeutic management, including the use of defibrotide, to optimize clinical outcomes.
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Ashley Jacks, PA-C
Fred Hutchinson Cancer Center Ashley Jacks, PA-C, is an APP at Fred Hutchinson Cancer Center in the Bone Marrow Transplant and Immunotherapy department in Seattle, Washington. She is a graduate of the University of Nevada School of Medicine Master of Physician Assistant Studies program who went on to complete a post-graduate physician assistant fellowship program at MD Anderson Cancer Center in Houston. When not partaking in clinical practice duties, Ashley enjoys spending time exploring the outdoor sights and scenes of the Pacific Northwest with her husband and son.
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